League of Legends (LoL) is a strategic, team-based online game where players control powerful champions in fast-paced battles to destroy the enemy's Nexus and achieve victory. This guide explores the game’s background, and specific gameplay mechanics, and focuses on the champion roles of Karthus and Anivia, providing detailed strategies for each. When you embark on your journey, mmowow items can lend a helping hand when you need help.

Game Background
Set in the world of Runeterra, League of Legends features an intricate lore with various regions and storylines. Karthus and Anivia are two champions from this universe, each with unique attributes and abilities.

Champion Overview: Karthus and Anivia
Karthus - The Deathsinger
Karthus is a mage who excels in dealing with persistent area-of-effect damage and has the unique ability to continue casting spells after dying. He is typically played in the mid-lane or as a jungler.

Role: Mage
Lane: Mid/Jungle

Abilities:

Passive - Death Defied: Upon dying, Karthus enters a spirit form, allowing him to continue casting spells for 7 seconds.
Q - Lay Waste: Karthus releases a delayed blast at a target location, dealing damage to nearby enemies. Deals double damage if it hits a single target.
W - Wall of Pain: Karthus creates a wall that slows and reduces the magic resistance of enemies who pass through it.
E - Defile: While toggled on, nearby enemies take continuous damage. Karthus restores mana per enemy killed.
R - Requiem: Karthus channels for 3 seconds to deal damage to all enemy champions, regardless of location.
Skill Order: Max Q first for damage, followed by E for consistent damage output, and W last, with points in R whenever possible.

Runes:

Primary: Domination

Dark Harvest (Snowball potential)
Cheap Shot (Increased damage)
Eyeball Collection (Scaling AP)
Ravenous Hunter (Healing)
Secondary: Sorcery

Presence of Mind (Mana sustain)
Last Stand (Increased damage at low health)
Item Build:

Core Items:

Liandry's Anguish (Damage over time)
Zhonya's Hourglass (Survivability)
Rabadon's Deathcap (AP boost)
Situational Items:

Morellonomicon (Grievous wounds)
Void Staff (Magic penetration)
Banshee's Veil (Magic resist)
Gameplay:

Early Game: Focus on farming and poking with Q. Use W to slow enemies and set up ganks.
Mid-Game: Use your R to assist in fights across the map. Position yourself to maximize damage with E and Q.
Late Game: In team fights, use your passive to continue dealing damage after dying. Aim to use R when multiple enemies are low.
Anivia - The Cryophoenix
Anivia is a mage with strong crowd control and burst damage, capable of zoning enemies and controlling fights. She is primarily played in the mid-lane.

Role: Mage
Lane: Mid

Abilities:

Passive - Rebirth: Upon taking fatal damage, Anivia transforms into an egg and will be reborn with full health if the egg survives for 6 seconds.
Q - Flash Frost: Anivia launches a sphere of ice that deals damage and stuns enemies it passes through. It explodes for additional damage and a stun when reactivated.
W - Crystallize: Anivia creates a wall of ice that blocks enemy movement.
E - Frostbite: Anivia blasts her target, dealing double damage if the target is chilled by Q or R.
R - Glacial Storm: Anivia creates a blizzard that deals damage and slows enemies. The storm increases in size over time.
Skill Order: Max E first for burst damage, followed by Q for poke and crowd control, and W last, with points in R whenever possible.

Runes:

Primary: Sorcery

Electrocute (Burst damage)
Manaflow Band (Mana sustain)
Transcendence (Cooldown reduction)
Scorch (Early game poke)
Secondary: Inspiration

Biscuit Delivery (Sustain)
Cosmic Insight (Cooldown reduction)
Item Build:

Core Items:

Rod of Ages (Scaling health, mana, and AP)
Archangel's Staff (Mana and AP)
Zhonya's Hourglass (Survivability)
Situational Items:

Morellonomicon (Grievous wounds)
Rabadon's Deathcap (AP boost)
Void Staff (Magic penetration)
Gameplay:

Early Game: Use Q to poke and farm. Utilize W to control enemy movement and set up kills.
Mid Game: Use R to zone and control fights. Combine Q and E for maximum burst damage.
Late Game: Position yourself to control team fights with your R and use W to block enemy engages or escapes.
Team Fight Tactics
Karthus:

Engaging: Use Wall of Pain to slow and debuff enemies. Position yourself in the middle of the fight to maximize E damage. If you die, use your passive to continue casting spells.
Objective Control: Use R to secure kills or assist teammates globally. Position aggressively to deal sustained damage.
Anivia:

Engaging: Use Flash Frost to poke and initiate. Follow up with Crystallize to control the battlefield and isolate targets.
Objective Control: Use Glacial Storm to zone enemies away from objectives. Use your wall to block paths and funnel enemies.
Recommended Team Compositions
Karthus:

Engage Comp: Pair with champions like Amumu or Malphite who can initiate fights and allow Karthus to follow up with his damage.
Poke Comp: Combine with poke champions like Xerath or Caitlyn to chip away at enemies before engaging.
Sustain Comp: Include champions like Soraka or Yuumi to provide healing and sustain for longer fights.
Anivia:

Control Comp: Pair with champions like Sejuani or Ornn who can provide additional crowd control and peel.
Burst Comp: Combine with burst champions like LeBlanc or Zed to quickly eliminate key targets.
Peel Comp: Include champions like Janna or Lulu to provide additional protection and peel for Anivia.
Advantages and Disadvantages
Karthus:

Advantages:

Global presence with R.
Consistent area-of-effect damage.
Strong in team fights, especially post-death.
Disadvantages:

Vulnerable to crowd control.
Requires good positioning.
High mana consumption.
Anivia:

Advantages:

Strong crowd control and zoning.
High burst damage.
Survivability with passive.
Disadvantages:

Skillshot-dependent.
Requires good positioning.
Vulnerable during egg form.
Practical Tips for Playing Karthus
Early Game:

Focus on farming with Q. Use W to set up ganks or avoid them.
Maintain vision control to avoid jungle pressure.
Mid Game:

Use R to assist in global fights. Position yourself to maximize your damage output.
Roam to other lanes and help secure objectives.
Late Game:

In team fights, prioritize positioning to deal maximum damage with E and Q.
Utilize your passive effectively by continuing to cast spells after dying.

Facing Gragas: Strategies for Karthus and Anivia in Early, Mid, and Late Game
In League of Legends, leaning against Gragas can be challenging due to his crowd control, burst damage, and sustain. Here’s a detailed guide on how to approach this matchup with Karthus and Anivia, covering early, mid, and late-game strategies, team fight tactics, and specific tips for Karthus based on his attributes and playstyle.

Early Game Strategies
Karthus:

Laning Phase:
Positioning: Stay at a safe distance to avoid Gragas’s Q (Barrel Roll) and E (Body Slam) which can harass and engage you.
Poking: Use Q (Lay Waste) to poke Gragas from a distance, focusing on landing isolated Qs for maximum damage.
Defensive Play: Use W (Wall of Pain) to slow Gragas if he engages with you, making it easier to dodge his follow-up abilities.
Farming: Focus on last-hitting minions with Q. If Gragas tries to engage, kite back and poke him with Q.
Anivia:

Laning Phase:
Positioning: Stay behind minions to avoid Gragas’s Q poke. Be ready to use Flash if Gragas lands a successful E-engage.
Poking: Use Q (Flash Frost) to poke and stun Gragas, and follow up with E (Frostbite) for burst damage.
Defensive Play: Use W (Crystallize) to block Gragas’s path if he tries to engage. It can also help in avoiding jungle ganks.
Farming: Use auto-attacks and Q to last-hit minions. Utilize R (Glacial Storm) to clear waves efficiently once you have it.
Mid Game Strategies
Karthus:

Roaming: Look for opportunities to roam and assist other lanes with your R (Requiem). Use W to set up ganks and slow enemies.
Objective Control: Use W to create zones of control around objectives like Dragon or Rift Herald. R can secure kills or assist in team fights globally.
Engaging: Use W to catch out-of-position enemies and follow up with Q and E (Defile) for sustained damage.
Anivia:

Wave Management: Utilize your R to quickly clear waves and create pressure in other lanes. This also allows you to roam effectively.
Roaming: Use your mobility to roam and assist other lanes with Q and E for burst damage. Your W can help trap enemies during ganks.
Combos: Continue to trade with Q > E combos. Use R to zone and control enemy movements in fights.
Late Game Strategies
Karthus:

Team Fights: Position yourself to deal maximum damage with E and Q. If you die, use your passive to continue dealing damage.
Objective Control: Use R to assist in securing kills across the map. Position aggressively to maximize damage output.
Peeling: Use W to slow and debuff enemies diving your backline.
Anivia:

Team Fights: Use R to create zones of control and damage. Position yourself to land Q > E combos on priority targets.
Objective Control: Use your W to block enemy engagement or retreats around objectives. R can zone enemies away from key areas.
Peeling: Use W and Q to protect your backline from diving enemies.
Team Fight Tactics
Karthus:

Engaging: Use Wall of Pain to slow and debuff enemies. Position in the middle of the fight to maximize E damage. If you die, continue casting spells with your passive.
Objective Control: Use Requiem to secure kills or assist teammates globally. Position aggressively to deal sustained damage.
Anivia:

Engaging: Use Flash Frost to poke and initiate. Follow up with Crystallize to control the battlefield and isolate targets.
Objective Control: Use Glacial Storm to zone enemies away from objectives. Use your wall to block paths and funnel enemies.
Practical Tips for Karthus in Real Gameplay
Early Game:

Focus on farming with Q. Use W to set up ganks or avoid them.
Maintain vision control to avoid jungle pressure.
Mid Game:

Use R to assist in global fights. Position yourself to maximize your damage output.
Roam to other lanes and help secure objectives.
Late Game:

In team fights, prioritize positioning to deal maximum damage with E and Q.
Utilize your passive effectively by continuing to cast spells after dying.

 Why Karthus is Recommended for Long-term Play
Karthus’s consistent damage output, global presence, and strong team fight capabilities make him an excellent champion for players to master. His unique ability to deal damage after death allows him to remain impactful even when focused by the enemy team. Karthus’s straightforward playstyle and significant impact in team fights make him a reliable choice for players looking to climb the ranks and contribute consistently to their team’s success. However, when some players choose to explore further and become familiar with a certain hero, some players will choose to buy lol items.

By understanding the strengths and strategies for playing Karthus and Anivia, and by implementing these tactics, you can effectively counter various champions and maximize your potential in different phases of the game. Karthus’s utility and reliability make him a particularly strong pick for players aiming to improve and succeed in League of Legends. I hope this guide helps you enhance your gameplay and achieve your goals on the Rift. Good luck, and have fun!