Natural compounds have been used for centuries in traditional medicine and have gained increasing attention in recent years due to their potential therapeutic properties. One such natural compound is Cis-Isolimonenol, which has the chemical formula C10H18O and the CAS number 22972-51-6. This compound is found in a variety of plants, including citrus fruits, and has been studied for its potential health benefits. In this blog post, SACH BIOTECH will provide a comprehensive overview of the properties of Cis-Isolimonenol, including its chemical structure, physical properties, and potential therapeutic applications.

Chemical Structure of Cis-Isolimonenol

Cis-Isolimonenol is a terpene alcohol that belongs to the family of monoterpenes. It is a colorless liquid with a boiling point of 204-206°C and a density of 0.89 g/mL. The molecular weight of Cis-Isolimonenol is 154.25 g/mol, and its chemical structure consists of a cyclohexene ring with a hydroxyl group and a methyl group attached to it. The compound also has a double bond between carbon atoms 1 and 2, which gives it its cis configuration.

Physical Properties of Cis-Isolimonenol

Cis-Isolimonenol has a characteristic odor that is similar to that of limonene, which is another terpene found in citrus fruits. The compound is soluble in organic solvents such as ethanol, ether, and chloroform but is insoluble in water. It has a refractive index of 1.472 and a specific gravity of 0.89. The compound is stable under normal conditions but can be oxidized by air or light, leading to the formation of other compounds.

Therapeutic Applications of Cis-Isolimonenol

Cis-Isolimonenol has been studied for its potential therapeutic properties, including its antimicrobial, anti-inflammatory, and antioxidant effects. Here are some of the potential therapeutic applications of Cis-Isolimonenol:

1. Antimicrobial Properties

Cis-Isolimonenol has been shown to have antimicrobial properties against a variety of microorganisms, including bacteria, fungi, and viruses. In a study published in the Journal of Essential Oil Research, Cis-Isolimonenol was found to have strong antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans. Another study published in the Journal of Agricultural and Food Chemistry found that Cis-Isolimonenol had antiviral activity against the herpes simplex virus.

2. Anti-inflammatory Properties

Cis-Isolimonenol has also been studied for its anti-inflammatory properties. In a study published in the Journal of Natural Products, Cis-Isolimonenol was found to inhibit the production of nitric oxide and prostaglandin E2, which are inflammatory mediators. Another study published in the Journal of Agricultural and Food Chemistry found that Cis-Isolimonenol had anti-inflammatory effects in a mouse model of acute lung injury.

3. Antioxidant Properties

Cis-Isolimonenol has been shown to have antioxidant properties, which can help protect against oxidative stress and damage. In a study published in the Journal of Agricultural and Food Chemistry, Cis-Isolimonenol was found to have strong antioxidant activity in vitro. Another study published in the Journal of Essential Oil Research found that Cis-Isolimonenol had protective effects against oxidative stress in a rat model of liver injury.

4. Other Potential Applications

Cis-Isolimonenol has also been studied for its potential anticancer, analgesic, and insecticidal properties. In a study published in the Journal of Natural Products, Cis-Isolimonenol was found to have cytotoxic effects against human cancer cell lines. Another study published in the Journal of Agricultural and Food Chemistry found that Cis-Isolimonenol had analgesic effects in a mouse model of pain. In addition, Cis-Isolimonenol has been shown to have insecticidal properties against the mosquito Aedes aegypti.

Conclusion

Cis-Isolimonenol is a natural compound found in citrus fruits that has been studied for its potential therapeutic properties. The compound has a unique chemical structure and physical properties, including its characteristic odor and solubility in organic solvents. Cis-Isolimonenol has been shown to have antimicrobial, anti-inflammatory, and antioxidant effects, as well as potential anticancer, analgesic, and insecticidal properties. While more research is needed to fully understand the therapeutic potential of Cis-Isolimonenol, the compound shows promise as a natural alternative to traditional pharmaceuticals.

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